[HTML][HTML] Injectable thermoresponsive hydrogels as drug delivery system for the treatment of central nervous system disorders: A review

E Bellotti, AL Schilling, SR Little, P Decuzzi - Journal of controlled release, 2021 - Elsevier
… viscous hydrogel forms a depot for the sustained release of … the treatment and management
of brain tumors, spinal cord and … containing neurotrophin 3 (NT-3) loaded microspheres on …

[HTML][HTML] Biocompatible copolymer formulations to treat glioblastoma multiforme

LCS Erthal, OL Gobbo, E Ruiz-Hernandez - Acta biomaterialia, 2021 - Elsevier
… PLGA (Poly Lactic-co-Glycolic Acid) PLGA nanofiber discs … covalently linked to two
camptothecin drug molecules, which … of having a sustained release of drugs, for example through

[HTML][HTML] Local delivery and glioblastoma: why not combining sustained release and targeting?

C Gazaille, M Sicot, P Saulnier, J Eyer… - Frontiers in Medical …, 2021 - frontiersin.org
… with BCNU is developed as microspheres, compressed into 1.4 cm … the hydrogel without
camptothecin (median survival of 36 days). … Zhao et al. have studied poly (lactic-co-glycolic acid) …

[PDF][PDF] SMART HYDROGEL-BASED INJECTABLE SYSTEMS FOR BREAST CANCER THERANOSTICS

HNC CARRÊLO - 2023 - run.unl.pt
Microspheres consist of a porous matrix that has the cargo … sustained release profile;
release of the decrease treatment efficiency and the patient's quality of life, especially when using

PLGA-based biodegradable microspheres in drug delivery: recent advances in research and application

Y Su, B Zhang, R Sun, W Liu, Q Zhu, X Zhang… - Drug …, 2021 - Taylor & Francis
Poly (lactic-co-glycolic acid) copolymer (PLGA) is one of the … consisting of anti-cancer drug
camptothecin (CPT) were … -19 cells due to their sustained release ability. In conclusion, PLGA …

[HTML][HTML] Design of biopolymer-based interstitial therapies for the treatment of glioblastoma

ES Pena, EG Graham-Gurysh, EM Bachelder… - International journal of …, 2021 - mdpi.com
… With sustained release of a drug locally, therapeutic … (PGA), and their copolymer form
poly(lactic-co-glycolic) acid (PLGA), … hydrogels without PLGA microspheres or PTX-loaded PLGA …

Long-acting therapeutic delivery systems for the treatment of gliomas

S Padmakumar, MM Amiji - Advanced Drug Delivery Reviews, 2023 - Elsevier
Cancer sticky hydrogel … Pediatric brain tumors are also one of the leading causes of pediatric
malignancies [11]. Pilocytic astrocytoma, considered to be the most common brain tumor in …

Engineered hydrogels for brain tumor culture and therapy

J Thakor, S Ahadian, A Niakan, E Banton… - Bio-design and …, 2020 - Springer
sustained release manner for efficient glioma chemotherapy. For this purpose, poly(lactic-co-glycolic
acid… beneficial for drug treatments as they can provide sustained release of different …

[HTML][HTML] PLGA–the smart polymer for drug delivery

N Surya, S Bhattacharyya - Pharmacy & Pharmacology, 2021 - rjraap.com
… biodegradable polymer is poly lactic-co-glycolic acid (PLGA) … the sustained release of drug
could cause apoptosis of tumour cell… drugs- camptothecin or vincristine. After injection into the …

Recent advances in drug delivery nanocarriers incorporated in temperature-sensitive Pluronic F-127–A critical review

RJ PJ, OS Oluwafemi, S Thomas, AO Oyedeji - Journal of Drug Delivery …, 2022 - Elsevier
… and nucleic acids and hydrophobic drugs (eg camptothecin) [10,11]… polymers eg. Poly (lactic
-co -glycolic acid), polyethylene … particles provided a sustained release of tobramycin sulfate …